双醛壳聚糖的制备及其对皮胶原纤维的交联作用

doi:10.19677/j.issn.1004-7964.2021.02.001

皮革科学与工程 ›› 2021, Vol. 31 ›› Issue (2): 1-5.doi: 10.19677/j.issn.1004-7964.2021.02.001

• 试验研究 • 下一篇

双醛壳聚糖的制备及其对皮胶原纤维的交联作用

黄婉丽¹, 杨紫涵¹, 王亚楠^1,2, 石碧^1,2,*

1.四川大学制革清洁技术国家工程研究中心,四川成都 610065;
2.四川大学皮革化学与工程教育部重点实验室,四川成都 610065

收稿日期:2020-10-22 出版日期:2021-04-28 上线日期:2021-03-30
通讯作者: *石碧（1958-）,男,教授,E-mail: shibi@scu.edu.cn,主要从事制革清洁技术研究。
作者简介:黄婉丽（1995-）,女,硕士生。
基金资助:
国家重点研发计划项目（2017YFB0308500）

Preparation of Dialdehyde Chitosan and its Application for Crosslinking Collagen Fiber

HUANG Wanli¹, YANG Zihan¹, WANG Yanan^1,2, SHI Bi^1,2,*

1. National Engineering Research Center of Clean Technology in Leather Industry, Sichuan University, Chengdu 610065, China;
2. Key Laboratory of Leather Chemistry and Engineering (Sichuan University),Ministry of Education, Chengdu 610065, China

Received:2020-10-22 Online:2021-04-28 Published:2021-03-30

摘要/Abstract

摘要： 用高碘酸钠氧化法制备了双醛壳聚糖（DCTS）。以高氧化度和低重均相对分子质量为评价指标,得到的较优制备条件为：壳聚糖脱乙酰度为95.1%,氧化初始pH为3.0,高碘酸钠与壳聚糖GlcN单元的物质的量比为1.1,氧化时间为6 h,氧化温度为20~25 ℃。将DCTS作为皮胶原纤维的交联剂,考察DCTS的氧化度对其交联性能的影响。DSC和压汞仪分析结果表明,随着DCTS氧化度的升高,皮胶原纤维的热变性温度提高,同时孔隙率降低,说明DCTS的交联作用逐渐增强。

关键词: 双醛壳聚糖, 高碘酸钠氧化, 胶原纤维, 交联

Abstract: Dialdehyde chitosan (DCTS) was prepared by periodate oxidation. In terms of high oxidation degree and low weight average molecular weight, the conditions of DCTS preparation were optimized as follows. The deacetylation degree of CTS was 95.1%. The initial oxidation pH was 3.0. The mole ratio of sodium periodate to GlcN unit of CTS was 1.1. The oxidation duration was 6 h, and the temperature was 20-25 ℃. DCTS was then used as a crosslinker of collagen fiber. The effect of oxidation degree of DCTS on its crosslinking performance was investigated. DSC and mercury intrusion porosimetry analysis showed that the thermal denaturation temperature of collagen fiber rose with the increase of oxidation degree, and the porosity of collagen fiber was reduced accordingly. These results suggested that the crosslinking performance of DCTS was enhanced with the increased oxidation degree of DCTS.

Key words: dialdehyde chitosan, periodate oxidation, collagen fiber, crosslinking

中图分类号:

TS521

黄婉丽, 杨紫涵, 王亚楠, 石碧. 双醛壳聚糖的制备及其对皮胶原纤维的交联作用[J]. 皮革科学与工程, 2021, 31(2): 1-5.

HUANG Wanli, YANG Zihan, WANG Yanan, SHI Bi. Preparation of Dialdehyde Chitosan and its Application for Crosslinking Collagen Fiber[J]. Leather Science and Engineering, 2021, 31(2): 1-5.

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双醛壳聚糖的制备及其对皮胶原纤维的交联作用

Preparation of Dialdehyde Chitosan and its Application for Crosslinking Collagen Fiber

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