Leather Science and Engineering ›› 2024, Vol. 34 ›› Issue (2): 1-6.doi: 10.19677/j.issn.1004-7964.2024.02.001

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Study on the Collagen Hydrogel of Fish Skin via Laccase- Protocatechuic Aldehyde Cross-linking

YANG Changkai1,2, LI Guoying1,2,*   

  1. 1. Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, Sichuan University, Chengdu 610065, China;
    2. National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, China
  • Received:2023-09-11 Revised:2023-11-20 Accepted:2023-11-22 Published:2024-04-01 Online:2024-03-07

Abstract: Fish skin collagen has greater application potential than mammalian proteins because it is not limited by the prevalence of Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. However, it is restricted by its poor mechanical properties and poor resistance to degradation. This work investigated the cross-linking mechanism, gel microstructure, mechanical properties and degradation resistance of collagen hydrogels prepared by the cross-linking of laccase (LAC) with protocatechuic aldehyde (PAL). Results showed that LAC could cross-link collagen to form a hydrogel. Meanwhile, the introduction of PAL enhanced the role of LAC in cross-linking collagen and improved the structural stability and degradation resistance of the resulting collagen hydrogels. The collagen cross-linked via LAC-PAL is an effective strategy for constructing collagen hydrogels.

Key words: hydrogel, fish skin, collagen, laccase, protocatechuic aldehyde

CLC Number: