Abstract: This scoping review assessed the current applications of wearable inertial measurement units (WIMU) for the evaluation of gait after total knee arthroplasty (TKA). Seven databases, including PubMed, EMBASE, MEDLINE, Web of Science Core Collection, CNKI, Wanfang Data and VIP, were searched for articles published between 2014 and 2023, using keywords related to “wearable inertial sensors”, “total knee arthroplasty”, and “gait analysis”. Two authors independently conducted the title and abstract reviews, completing full-text screenings, quality evaluations, and full-text data extractions, and any inconsistencies were resolved through negotiation. A total of 16 articles were ultimately included, and the literature quality score was generally low. There was considerable variation among these studies regarding the number of patients, sensor schemes and experimental schemes. The research mainly focused on the short-term longitudinal kinematics parameter evaluation, and lack in-depth investigations of the rules of gait parameters based on WIMU evolving in response to disease progression. Despite challenges in current research, the use of WIMU for remote gait data collection in the daily lives of TKA patients still holds great promise in the future.