Abstract: As China enters a stage of high-quality development, industrial upgrading is accelerating, which has put forward higher requirements for the development of vocational education, especially for the construction of double-qualified teachers. Teacher enterprise practice is an important measure to promote the combination of theory and practice, and improve teachers' ability and quality. It is also an important basis for promoting the integration of industry and education, school-enterprise cooperation, and promoting teaching reform and classroom revolution. This topic is about the leather shoe industry through field visits, questionnaire survey and studying the leather shoe industry vocational education teacher in the enterprise practice, including planning, organization form, implementation plan, effect evaluation, evaluation method, existing problems, etc. By summarizing the concise analysis, we combed out the teachers’ position, responsibilities and collaborative mode in the enterprise practice during deepening the process of government, enterprise and industry. This article will offer the support for promoting the overall abilities of teachers and transformation and upgrading of leather shoe industry.