Abstract: The creative transformation from “Ideological and Political Course” to “Ideological and Political Education in Curriculum” is a major and long-term issue faced by colleges and universities. In the process of transformation, how to integrate the content of ideological and political education naturally according to the content and form of professional teaching courses is the key to solve the problem. Taking the design course “Creative Design of Fashion Handbags” as an example, it chooses the cultural resources investigation of local museums as the way to combine the professional teaching with the ideological and political education, and adopts the forms of guide education, classified investigation, design report and experience exchange, which not only completes part of the teaching and research objectives of the professional teaching course, but also integrates the content of ideological and political education naturally by getting the core values of Chinese socialism playing a leading role in the teaching process , thus it can be regarded as a beneficial exploration of ideological and political education in university curricula.