Abstract: In the evaluation of genuine leather for office furniture, odor is one of the important indicators for its quality classification. This article used electronic nose technology and odor method, combined with the current leather odor detection method standards, to conduct experimental analysis on three commonly used leather samples with obvious odors, and explored the correlation and differences between electronic nose technology and subjective evaluation, in order to provide better ideas and directions for the development of leather odor detection methods for office furniture. The results showed that there were differences in the relative contents of alcohol, aldehyde, ether, and short chain alkane components among the three selected genuine leather samples. Principal component analysis was conducted on sample 2 of genuine leather, and the results showed that its odor was closely related to the relatively high contents of alcohol, aldehyde, ether components and short chain alkane components such as methane. We conducted 100 effective wet state electronic nose experiments on sample 2 and developed a leather odor standard for the electronic nose method, which can provide guidance for new technology detection of leather odor.